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The theory of concepts advanced in the dissertation aims at accounting for a) how a concept makes successful practice possible, and b) how a scientific concept can be subject to rational change in the course of history. Traditional accounts in the philosophy of science have usually studied concepts in terms only of their reference; their concern is to establish a stability of reference in order to address the incommensurability problem. My discussion, in contrast, suggests that each scientific concept consists of three components of content: 1) reference, 2) inferential role, and 3) the epistemic goal pursued with the concept's use. I argue that in the course of history a concept can change in any of these three components, and that change in one component—including change of reference—can be accounted for as being rational relative to other components, in particular a concept's epistemic goal.

This semantic framework is applied to two cases from the history of biology: the homology concept as used in 19th and 20th century biology, and the gene concept as used in different parts of the 20th century. The homology case study argues that the advent of Darwinian evolutionary theory, despite introducing a new definition of homology, did not bring about a new homology concept (distinct from the pre-Darwinian concept) in the 19th century. Nowadays, however, distinct homology concepts are used in systematics/evolutionary biology, in evolutionary developmental biology, and in molecular biology. The emergence of these different homology concepts is explained as occurring in a rational fashion. The gene case study argues that conceptual progress occurred with the transition from the classical to the molecular gene concept, despite a change in reference. In the last two decades, change occurred internal to the molecular gene concept, so that nowadays this concept's usage and reference varies from context to context. I argue that this situation emerged rationally and that the current variation in usage and reference is conducive to biological practice.

The dissertation uses ideas and methodological tools from the philosophy of mind and language, the philosophy of science, the history of science, and the psychology of concepts.

The present paper discusses Kitcher’s framework for studying conceptual change and progress. Kitcher’s core notion of reference potential is hard to apply to concrete cases. In addition, an account of conceptual change as change in reference potential misses some important aspects of conceptual change and conceptual progress. I propose an alternative framework that focuses on the inferences and explanations supported by scientific concepts. The application of my approach to the history of the gene concept offers a better account of the conceptual progress that occurred in the transition from the Mendelian to the molecular gene than Kitcher’s theory.

The paper works towards an account of explanatory integration in biology, using as a case study explanations of the evolutionary origin of novelties—a problem requiring the integration of several biological fields and approaches. In contrast to the idea that fields studying lower level phenomena are always more fundamental in explanations, I argue that the particular combination of disciplines and theoretical approaches needed to address a complex biological problem and which among them is explanatorily more fundamental varies with the problem pursued. Solving a complex problem need not require theoretical unification or the stable synthesis of different biological fields, as items of knowledge from traditional disciplines can be related solely for the purposes of a specific problem. Apart from the development of genuine interfield theories, successful integration can be effected by smaller epistemic units (concepts, methods, explanations) being linked. Unification or integration is not an aim in itself, but needed for the aim of solving a particular scientific problem, where the problem’s nature determines the kind of intellectual integration required.

This paper uses an example from biology, the homology concept, to argue that current versions of the causal theory of reference give an incomplete account of reference determination. It is suggested that in addition to samples and stereotypical properties, the scientific use of concepts and the epistemic interests pursued with concepts are important factors in determining the reference of natural kind terms.

Our understanding of subjunctive conditionals has been greatly enhanced through the use of possible world semantics and, more precisely, by the idea that they involve variably strict quantification over possible worlds. I propose to extend this treatment to ceteris paribus conditionals – that is, conditionals that incorporate a ceteris paribus or ‘other things being equal’ clause. Although such conditionals are commonly invoked in scientific theorising, they traditionally arouse suspicion and apprehensiveness amongst philosophers. By treating ceteris paribus conditionals as a species of variably strict conditional I hope to shed new light upon their content and their logic.

The purpose of the paper is twofold. I first outline a philosophical theory of concepts based on conceptual role semantics. This approach is explicitly intended as a framework for the study and explanation of conceptual change in science. Then I point to the close similarities between this philosophical framework and the theory theory of concepts, suggesting that a convergence between psychological and philosophical approaches to concepts is possible. An underlying theme is to stress that using a non-atomist account of concepts is crucial for the successful study of conceptual development and change—both for the explanation of individual cognitive development and for the study of conceptual change in science.

One of the distinctive properties of conscious states is thepeculiar self-awareness implicit in them. Two rival accounts of this self-awareness are discussed. Accordingto a Neo-Brentanian account, a mental state M is conscious iff M represents its very own occurrence.According to the Higher-Order Monitoring account, M is merely accompanied by a numerically distinctrepresentation of its occurrence. According to both, then, M is conscious in virtue of figuring in a higher-ordercontent. The disagreement is over the question whether the higher-order content is carried by Mitself or by a different state. While theNeo-Brentanian theory is phenomenologically more attractive, it isoften felt to be somewhat mysterious. It is argued (i) that the difference between the Neo-Brentanian andHigher-Order Monitoring theories is smaller and more empirical than may initially seem, and (ii) that theNeo-Brentanian theory can be readily demystified. These considerations make it prima faciepreferable to the Higher-Order Monitoring theory.

This article introduces and discusses from a philosophical point of view the nascent field of neuroeconomics, which is the study of neural mechanisms involved in decision-making and their economic significance. Following a survey of the ways in which decision-making is usually construed in philosophy, economics and psychology, I review many important findings in neuroeconomics to show that they suggest a revised picture of decision-making and ourselves as choosing agents. Finally, I outline a neuroeconomic account of irrationality.

Duhem's and Quine's holistic theses, when properly understood, allow methodologically responsible ways of resolving a conflict between a theoretical system and experience; they only deny the possibility of doing it in an epistemically persuasive way. By developing a "string" model of scientific tests I argue that the pattern of interaction between the elements of a theoretical system arising in response to multiple adverse data can be helpful in locating a "weak spot" in it. Combining this model with anti-holistic arguments of Popper, Greenwood, and Lakatos significantly reinforces their joint power